References & formulas

Mass-transfer area coefficient (KoA)

The KoA is a membrane performance characteristic, and is defined as the membrane theoretical clearance capacity at infinite blood and dialysate flow

Leypoldt JK, Cheung AK, Agodoa LY, Daugirdas JT, Greene T, Keshaviah PR. Hemodialyzer mass transfer-area coefficients for urea increase at high dialysate flow rates. The Hemodialysis (HEMO) Study. Kidney Int. 1997 Jun;51(6):2013-7

PMID: 9186896.

Chelamcharla M, Leypoldt JK, Cheung AK. Dialyzer membranes as determinants of the adequacy of dialysis. Semin Nephrol. 2005 Mar;25(2):81-9

PMID: 15791559.

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Disclaimer: Extracorporeal therapies are complex and require a full understanding of technical and clinical considerations. Adequator is not a substitute for clinical or technical reasoning. No medical decision should be made solely on this program’s results.